Good graphics, but not such a good "trailer"
I think as a trailer, this could have perhaps been more informative. Trailers should seek to inform the viewer about the characters, themes and plot contained within a story. As far as I can tell, this does not. All it really tells the viewer is that Fibble becomes cursed with Sin, and chaos ensues.
The viewer isn't shown show much about any of the other characters that you mentioned in the description "dolatry, Skitzo the 1920's killer bear, Promiscuous, Anxiety, and Suicide." I think this is a missed opportunity.
If you introduce these characters, and perhaps included more specifics about the story, then I think the trailer would be more successful. Currently it just looks more like a montage of action scenes.
Good job on the animation and drawing though, I look forward to the series.